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Associated Disorders

 

Children and adolescents with type 1 diabetes may be at increased risk of a number of other autoimmune Disorders. As in type 1 diabetes, these Disorders occur when the body’s immune system, which normally protects us from infection, begins to attack healthy cells.


Coeliac Disease

Coeliac disease is a condition where the lining of the small intestine is damaged due to a sensitivity to a protein in food, called gluten. Coeliac disease occurs in approximately 6% of children with type 1 diabetes. Symptoms can include abdominal discomfort, weight loss, anaemia, diarrhoea and unexplained hypoglycaemia. However some children have no symptoms at all. A blood test for coeliac disease is usually carried out during annual screening. A raised level of certain antibodies in the blood may suggest that a small bowel biopsy is needed to confirm diagnosis. The management of diabetes and coeliac disease includes the lifelong removal of all gluten from the diet.

More information about the dietary management of coeliac disease available January 08..


Thyroid Conditions

Children and adolescents with type 1 diabetes, may be at increased risk of either an under-active (hypothyroidism) or over-active thyroid (hyperthyroidism). Thyroid tests are usually carried out during annual screening.

Hypothyroidism
An under-active thyroid autoimmune condition occurs in approximately 3-5% of children and adolescents with diabetes. Signs and symptoms may include an enlarged thyroid gland (goitre), tiredness, poor growth, intolerance to cold and sometimes problems with diabetes control. Hypothyroidism is diagnosed via a blood test and is easily treated with thyroid tablets.

Hyperthyroidism
An over-active thyroid autoimmune condition may also occur more frequently in children and adolescents with diabetes, but is less common than hypothyroidism. Signs and symptoms may include unexplained weight loss, shakiness, fast pulse, heat intolerance, protruding eyes and sometimes problems with diabetes control. Hyperthyroidism is diagnosed via a blood test and is treated with anti-thyroid tablets.


Other conditions

Vitiligo
Vitiligo is a condition of the skin that results in a loss of pigment causing white spots on the skin. Vitiligo affects approximately 6% of children and adolescents with type 1 diabetes. There are no significant side effects of this condition and at present there is no satisfactory treatment available.

Addisons Disease
Addisons disease is an autoimmune condition of the adrenal glands affecting up to 2% of children and adolescents with diabetes. Signs and symptoms include unexplained frequent hypos and reduced insulin requirements, skin colour changes, tiredness and weight loss. Addisons disease is diagnosed via a special test and is treated with lifelong medication. If Addisons disease is suspected, diagnosis and treatment is urgent.